The Science & Justice Research Center at the University of California, Santa Cruz is a globally unique endeavor that innovates experimental spaces, engages in collaborative research practices, and fosters emerging alliances between seemingly disparate sectors, disciplines and communities. Biomedical innovation, species extinction, toxic ecologies, healthcare reform, and many other contemporary matters of concern provoke questions that traverse multiple intellectual, institutional and ethico-political worlds. Science & Justice generates modes of inquiry and empirically rigorous research that address these enormous challenges and support livable worlds. The Center is home to the Science and Justice Working Group, graduate training programs and sponsored research projects. The initiative builds on the UCSC campus’ historic commitments to socioecological justice and strengths in science studies and interdisciplinary research.