Nov 27, 2012 | Climate Data, Dams, and Water Demand: A Cross-Disciplinary Conversation

Science & Justice Working Group Meeting

November 27, 2012, 4:00-6:00pm

Engineering 2, Rm. 599

Panelists:

Ruth Langridge: Legal Studies/ Politics Department, UCSC

Lori Pottinger: International Rivers Network

Bruce Daniels: Earth and Planetary Sciences, UCSC; Soquel Water District Board of Directors

Decades of anti-dam activism around the world have generated a greater public awareness of the social and ecological consequences of large dams. But urbanization and increasing fears over the hydrologic effects of climate change have slowed this anti-dam momentum. Climate models play a crucial role in the decision-making process, meaning that an understanding of the limits and possibilities of these models is more important than ever. This event addresses this problem by bringing together a water policy analyst, an advocate for healthy rivers, and a climate modeler to explore the relationship between hydrologic climate modeling and regional water resource planning. The event will explore how data are constructed, analyzed, and used to make water resource planning decisions; what challenges arise in this process for scientists, policy makers, and everyday people in affected watersheds; and what possibilities for social and environmental justice arise from a better understanding of these factors.

We will hear from Ruth Langridge, an expert on water law and policy in the Politics and Legal Studies Departments at UCSC; Lori Pottinger, an advocate for healthy rivers with the International Rivers Network in Berkeley; and Bruce Daniels, a PhD Candidate working on hydroclimatology in the Earth and Planetary Sciences Department at UCSC and a member of the Soquel Water District Board of Directors. The event will explore how data are constructed, analyzed, and used to make water resource planning decisions; what challenges arise in this process for scientists, policy makers, and everyday people in affected watersheds; and what possibilities for social and environmental justice arise from a better understanding of these factors.

Co-Sponsored by the UCSC Department of Anthroplogy

Nov 15, 2012 | We are all lichens: How symbiosis research has reconstituted a new realm of individuality

Scott Gilbert (Howard A. Schneiderman Professor Swarthmore College)

UCSC Philosophy Department Colloquium

Thursday, November 15, 4 – 6 pm. Humanities 1, rm. 210

The notion of the “biological individual” is crucial to studies of genetics, immunology, evolution, development, anatomy, and physiology. Each of these biological sub-disciplines has a specific conception of individuality, which has historically provided conceptual contexts for integrating newly acquired data. During the past decade, nucleic acid analysis, especially genomic sequencing and high-throughput RNA techniques, has challenged each of these disciplinary definitions by finding significant interactions of animals and plants with symbiotic microorganisms that disrupt the boundaries which heretofore had characterized the biological individual. Animals cannot be considered individuals by anatomical, or physiological criteria, because a diversity of symbionts are both present and functional in completing metabolic pathways and serving other physiological functions.

Similarly, these new studies have shown that animal development is incomplete without symbionts. Symbionts also constitute a second mode of genetic inheritance, providing selectable genetic variation for natural selection. The immune system also develops, in part, in dialogue with symbionts, and thereby functions as a mechanism for integrating microbes into the animal-cell community. Recognizing the “holobiont”—the multicellular eukaryote plus its colonies of persistent symbionts– as a critically important unit of anatomy, development, physiology, immunology, and evolution, opens up new investigative avenues and conceptually challenges the ways in which the biological sub-disciplines have heretofore characterized living entities.

COLLOQUIUM CO-SPONSORED BY:

History of Consciousness Department, Center for Cultural Studies, and Science & Justice Working Group

Nov 13, 2012 | When Does Personhood Begin? The Science and the Rhetoric

Renowned developmental biologist Scott Gilbert (Swarthmore) joins us to discuss the science and rhetoric of personhood from a cross-disciplinary perspective. The argument that a potential human adult should be given the status of "person" from the moment of conception is being frequently made by people who wish to make abortion and human stem cell research illegal. While "personhood" is a cultural and not a scientific category, biology is often being used to justify such claims. Biologists, however, have not reached consensus on this issue, and this talk will discuss some of the places where different groups of biologists have claimed "personhood" begins. These include fertilization, individuation/gastrulation (when the embryo can no longer form twins), the acquisition of the human-specific EEG pattern, and birth. The rhetoric surrounding the fertilization issue concerns the photographs of prenatal life and the cultural representation of DNA as our soul or essence.

Cosponsored by the Molecular, Cellular, and Developmental Biology Department

November 13, 2012 | 4:00-6:00 PM |Engineering 2, Room 599

Scott Gilbert, "When Does Personhood Begin?: The Science and the Rhetoric"
SJWG Rapporteur Report
13 November 2012
Rapporteur: Martha Kenney, History of Consciousness
Scott Gilbert (Swarthmore) spoke to us about public misconceptions about the science of when
life begins. He adapted this talk from an invited presentation he gave at The Vatican in 2007. He
raised a number of erroneous “facts” that give people the impression that scientists support the
idea that life and therefore personhood begins at fertilization. For example, many people believe
that all the instructions for development and heredity are already present in a fertilized egg.
More broadly DNA is often presented as tantamount to a “soul” or “essence.” To illustrate this
point Gilbert showed us car ads that were predicated on a deterministic concept of DNA. A
Toyota, for example, was advertised as having “a great set of genes.” In order to counter this
myth, Gilbert described new research from epigenetics and microbiome biology that shows many
of our fundamental bodily and behavioral characterizes are determined by the environment, not
just by genes.

He also discussed the misconception that an embryo is an autonomous entity and fully protected
inside the womb, explaining that for every 20 eggs fertilized only 6.2 become a fetus (at 8
weeks). Furthermore teratogenic compounds threaten fetal development and viability (Gilbert
argued that reducing teratogenic compounds in the environment might be a common project for
people on both sides of the abortion debate). The popularity of Lennart Nilsson’s photographs of
fetuses (actually abortuses) contributes to the misconception that fetuses are autonomous entities
by showing them floating outside of a woman’s body. The final myth that Gilbert addressed is
that scientists agree when personhood begins; there is, in fact, no such consensus and, he argued
that the question of personhood may not be a scientific question at all. However, Gilbert felt that
science does have something important to say about embryo/fetus development, which should
not be misconstrued in public discourse.

During the Q&A period Jenny Reardon wondered how biologists can participate in debates
around abortion and embryo research without calling upon science as the authoritative discourse.
I.e. “Science says x, therefore x.” Martha Kenney followed up on this question by asking
Gilbert: “If you consider images that are contributing the public discourse about embryo research
and abortion to be scientifically misleading, what images do you feel better represents your
knowledge of embryos and fetuses that is grounded in your own experience as a developmental
biologist.” Gilbert described a “gorgeous” colored MRI image he used for the front cover of his
textbook Developmental Biology; he explained that he had to keep telling the publishers to zoom
out on the image so that the fetus would not appear to be floating in space. Listening to Gilbert’s
passion for this image offered us a way to think out of the “science says” dilemma and into a way
of doing a politics of representation from within our professional practices. Donna Haraway
commented that a central problem with the abortion debates was that both sides want to ensure
that persons were protected from death. She argued that death is not the greatest tragedy and that
we need to learn how to kill well (not just protect life). For Haraway, the politics were not (only)
in getting the science right, not only in the images and rhetoric we traffic in, but the ways that
entities are protected and made killable within these moral and scientific discourses. The Q&A
period opened up Gilbert’s talk beyond the question of what science has to say in the abortion
and embryo research debates, to wider questions of representation, ethics, and epistemic
authority in a complex social and scientific landscape.

Nov 08, 2012 | Democracy Deluge: End Games of Science and Politics – Jenny Reardon

Jenny Reardon, Science & Justice Research Center Co-Director and Associate Professor of Sociology

Sociology Department Colloquium

Monday, November 26, 2012

12:30-2:00PM

301 College 8

Today ideals of participatory democracy that have long grounded Euro-American imaginaries of truth and freedom play important structuring roles in the natural sciences.  This represents a dramatic change for a domain of human activity that in the 20th century built its credibility largely through circumscribing itself as apolitical. While some celebrate these developments as part of the new spring for democracy, might this “unnatural” spread suggest a different reading?  This talk takes up this question through an analysis of a decade-long effort to render genomics democratic.  It explores what the rise of the “democratic genome” reveals about the limits of dominant narratives of “science and politics,” and what it might tell us about contemporary practices and conditions of democracy, justice and knowledge.

Oct 27, 2012 | Rethinking Development in Light of Climate Change

Interdisciplinary Development Working Group

Saturday October 27, 2012

9AM-5:30PM 

Oakes College

Invited speaker: Dr. Hallie Eakin, School of Sustainability, Arizona State University.

Increasingly climate change impacts have called into question the sustainability of development policies and practices. At the same time, development efforts share many of the goals of climate change adaptation and mitigation. Scholars and practitioners in both areas have recognized the need for more collaboration across these two fields to address the critical challenge of integrating development planning and climate action in ways that promote positive synergies and avoid past failures. This conference brings together scholars from a range of disciplines to explore to what extent the awareness of climate change causes and impacts is transforming development theories and practices.

For more information about this event please click here.

About the Interdisciplinary Development Working Group (IDWG): IDWG at UCSC provides a forum for faculty and students from all disciplines to discuss issues of development.  Our sessions center around members’research, close readings of selected texts, and presentations from invited guests. We engage with several of the sub-themes in development such as rural/urban dynamics, environmental change, social justice, natural resource management, and international  governance.

This event is made possible through the support of CGIRS, the Science and Justice Working Group, the Sociology Department and the Environmental Studies Department at UCSC.

 

Please direct any questions to idwg@ucsc.edu

Oct 25, 2012 | Enacting Multiple Salmon: Conversation across disciplinary practices

Science & Justice Working Group Meeting

October 25, 2012

2:00-4:00 PM

Oakes Mural Room

This event brings together different accounts of salmon, some from social scientists and some from natural scientists who each will describe, and reflect upon how ‘their’ salmon is constituted, first in describing their particular research on questions of wild and domestic salmon in the US, and in then in a public conversation with each other and with the audience. We will hear from Robin Wapless, from NOAA in Seattle, from Rachel Barnett-Johnson from the Biology department at UCSC, from John Law a sociologist at the Open University in the UK, and from Marianne Liene, an anthropologist from the University of Oslo. Together, these scientists know salmon through widely different practices, from salmon hatcheries in California, to aquaculture sites in Norway, from laboratories, from textbooks, and from scientific articles and environmental regulation.

What are the defining traits of the salmon, and what distinctions do they look for? How were they attracted to salmon, and what are the practices through which they come to know salmon? What material, historical, and perhaps ethical entanglements are involved in the practices through which salmon is rendered known?

A special focus is on the notion of the wild; and its semi-domesticated other: What is a wild salmon, and how is it different from a hatchery salmon or a farmed salmon? How can we contribute to an environment that accommodates and nurtures different kinds of salmon?

This is not so much a debate about what salmon really is, as a dialogue across disciplines about all the different forms that are involved in our shared, but different, efforts to know the world we all inhabit.

Co-sponsored by the University of Oslo and the UCSC Environmental Studies and Anthropology Departments.

Oct 09, 2012 | Ethnicity and Security: The Wen Ho Lee Case

Science & Justice Working Group Meeting with Jeffrey Bussolini (CUNY)

The treatment and legal case of Taiwanese-American physicist Wen Ho Lee is a remarkably instructive account of the troublesome intersecting dynamics of ethnicity and security in US national security institutions on the eve of the September 11th transformations. Perhaps most shocking is that some of the same techniques that became notorious after 9/11 (sensory deprivation, techniques of humiliation through shackling and temperature control) were previewed in Lee's treatment. In this respect, and in the mechanics of the case itself which are still poorly understood, the Lee case serves as an invaluable instance of what Foucault would call "the history of the present" in which the techniques of the post-9/11 security state were not simply created out of whole cloth, but were the amplifications of practices that had already been developed within US security and justice systems.

Continue Reading Oct 09, 2012 | Ethnicity and Security: The Wen Ho Lee Case

Sept 27, 2012 | Genomics Gets Personal: Property, Persons, Privacy

Introduction by David Haussler, Director of the UCSC Center for Biomolecular Science & Engineering and the UCSC Cancer Genomics Hub). 

Panelists:

Gail P. Jarvik, M.D., Ph.D., Head, Division of Medical Genetics, The Arno G. Motulsky Endowed Chair in Medicine & Professor of Genome Sciences, University of Washington Medical Center

Robert Cook-Deegan, M.D., Research Professor, Genome Ethics, Law & Policy, Duke University, Director, Center for Genome Ethics, Law and Policy, Duke Institute for Genome Sciences & Policy, Author of Gene Wars: Science, Politics and the Human Genome Project

John Wilbanks, Director, Sage Bionetworks, Director, Consent to Research project (CtR), Co-founder of the Access2Research petition
Senior Fellow in Entrepreneurship at the Ewing Marion Kauffman Foundation

Ryan Phelan, Founder, and former CEO, DNA Direct by Medco
Board member, Personal Genome Project, Founder Direct Medical Knowledge, Founding Executive Director of Planetree

Roundtable discussion moderated by Jenny Reardon, Director of the Science & Justice Research Center and Professor of Sociology at UC Santa Cruz.

Tremendous advances in sequencing technologies have transformed genomes into a valuable new source of data about the biology of individuals. While these new data promise a revolution in medical care, more immediately they pose fundamental new ethical, social and legal questions about ownership and control of our bodies and their molecular constituents.

• To what extent are genomes the property of persons, and thus subject to their control?

• To what extent should genomes be shared in pursuit of medical breakthroughs or profit by others?

Please join a panel of experts to explore these questions and offer insights on how we can advance personal genomics within ethical and legal frameworks that respond to these fundamental questions about individual rights, property, and the nature of public goods in a genomic age.

A  special event featuring a panel discussion on the ethical and legal questions around personal genomics, hosted at UCSF Mission Bay Campus Byers Auditorium at Genentech Hall, 600 16th Street, San Francisco.

ARCHIVE VIDEO

"Genomics Gets Personal: Property, Persons, Privacy"
SJWG Rapporteur Report
27 September 2012
Reporter: Martha Kenney
“Genomics Gets Personal: Property, Persons, Privacy” took place at UCSF’s Mission Bay
Campus on September 27th, 2012. Renowned Bioinformatics researcher David Haussler, in his
introduction to the event, explained that in the next phase of genomics research that the hardest
challenges will not be the technological or medical problems but the social issues. He suggested
that interdisciplinary initiatives like the Science & Justice Research Center are necessary to
investigate and address these social issues. Jenny Reardon, the chair of the proceedings,
introduced the topic of personal data by reminding the audience that not long ago there was no
such thing as “personal data.” We did not grow up with the idea of personal data, but in the age
of Facebook our lives are not only mediated by data but our bodies have become new, potentially
valuable, sources of data. The Science & Justice Research Center has been experimenting with
bringing novel groups of interdisciplinary researchers together to address these novel problems.
This event convened a panel of four world-class medical and legal experts from the public and
private sectors around two questions unique to problems that emerge from the rise of “personal
data”:

• To what extent are genomes the property of persons and subject to their control?
• To what extent should genomes be shared with others for the purpose of medical
breakthroughs or profit?

Prof. Reardon posed a question to each of the panelists that drew on their unique perspectives on
personal genomics. Through the course of the discussion it became clear that the speakers had
differing opinions on key issues that were based in their personal experience with genomics and
how they were positioned in the field. For example, on the topic of citizens having access to
their own genome sequences for diagnostic purposed, there were critical difference between the
different responses.

Gail Jarvik spoke about her practice of finding actionable genes for clinical intervention through
targeted exome sequencing rather than genome sequencing. This approaches is less expensive
and doesn’t return results for genetic conditions that clinicians are not testing for. The data is not
returned to the patient or their doctor because of the risk of misinterpretation. John Wilbanks,
Director of Sage Bionetworks, however, argued that patients have a right to their data and that
taking the data out of the hands of academics needs to become a more viable alternative.
Consumer health advocated Ryan Phlean said that that the opinion that genetic data is too
dangerous and confusing for public consumption is flawed. When there are good ways to
interpret genomic data accessible online genomic data will be useful to the public. Robert Cook-
Deegan, Professor of Genome Law, Health and Policy at Duke University, agreed that people are
becoming less tolerate to the older model where the doctor acts as an intermediary between
medical tests and the patients, but unmediated access to data for patients is only one of the
competing models doctors have to choose between as genomic sequencing becomes more
prevalent.

Questions of informed consent and patients as research partners also played a prominent role in
the discussions. Robert Cook-Deegan referenced the article, “Glad you asked: Participants'
Opinions of Re-Consent for dbGaP Data Submission” as evidence that patients prefer to be asked
when their data is used for a purpose different than the original study, but once asked they are
positively inclined to share their data. Gail Jarvik, who was one of the co-authors on that article,
cautioned that the patient sample was very homogenous, containing mostly white middle-class
Americans. The question of homogeneity is an important one for both scientific and ethical
questions. John Wilbanks joked that scientists he worked with thought they would “find the
Apple gene” because their sample population was all affluent, white men who are the first to buy
the next iPhone. While Ryan Phlean suggested that this is the demographic of “early adopters”
and will change as the technologies become more ubiquitous, Robert Cook-Deegan cautioned
that we should revisit the connection between genetics and eugenics in this context. Different
groups are and will be experiencing the risks and benefits of these technologies in different ways.
This point was echoed during the open question period by Kate Darling, a graduate student in
Medical Sociology at UCSF, who noted that people are drawn into medical contexts in highly
varied, uneven, and contradictory ways. A prison inmate experiences genomics differently that
someone who pays 23andMe for genomic sequencing. Paying attention to this uneven landscape
of medicalization is key for doing bioethics in an age of personal genomics.

It was clear from the questions and varied responses that the territory of personal genomics is
still very much in formation. Questions of sharing and privacy, consent and re-consent, diversity
and inequality, paternalism vs. partnership vs. personal knowledge, and who should profit from
genomic data are currently at stake and could be addressed in multiple different ways. Forums
such as this event are an important part of building a future for personal genomics that takes into
account the social issues that arise with the new genomic technologies and is informed by
different situated (sometimes contrasting) perspectives.

Aug 19, 2012 | Modelling pigs and humans: Exploring the practices of models across sciences

Wednesday October 19, 2011

Engineering 2, Room 599

PhD Fellow Vibeke Pihl, Medical Centre for Science and Technology Studies, Department of Public Health, University of Copenhagen.

Vibeke Pihl’s research addresses how connections between humans and animals are shaped in contemporary biomedical research on human health. During an ethnographic multi-sited fieldwork, Vibeke has followed a group of Danish biomedical researchers working to establish a pig model for human obesity surgery. In biomedicine, the pig is increasingly established as a preferred model organism in biomedical research on human obesity due to an argued biological resemblance between pigs and human anatomy and physiology. The topic of the SJWG event concerns an analysis of how the use of pigs as models for humans does not rest solely on biological connections, but requires social, moral, economical and cultural connections to support the choice of the pig as the appropriate model for obese human bodies. In addition, the presentation will address how models are practised in biomedical science and social science. Drawing upon fieldwork, the presentation will focus on how the analysis of the biomedical researchers’ establishment of a pig model prompt a simultaneous crafting of a social scientific model of human-animal relations. Vibeke asks which connections between humans and pigs are included and excluded in the research practices of biomedical scientists’ and the practices of social scientists like her own. With this presentation, Vibeke wants to provide an opening for a stronger mutual engagement between researchers across sciences working with animals as models of humans.

Fall 2012 | Science & Justice Working Meetings

John Kadvany: A Very Short Introduction to Risk

Wednesday, October 5, at our normal time and place (Eng 2 599. 4:15-6:15).

John Kadvany will join us to discuss the concept of risk. Oxford University Press recently published John’s book on risk, entitled Risk: A Very Short Introduction. Given that so many of us in the group are interested in thinking well about risk–whether in the context of genomics or the climate or engineering design–we are particularly pleased to have John kick the year off.

Click here for an introduction to some of John’s ideas about risk.

Kadvany often works on project teams organized by an engineering company in charge of a large public works project. His role is to design and help implement a decision process in which engineers, external stakeholders, lawyers and regulators work their collective way through multiple competing options in an efficient, democratic and cooperative manner. He will design an analytical frameworkthat’s useful all around including the measurement techniques which can be used to accommodate relevant models, data, and professional or lay judgment of various qualities. Often these processes lead to a group “opinion survey”, a combined technical-policy document which summarizes stakeholder perspectives. His methods combine the analytical techniques of multiple values decision analysis with the approaches developed in the last two decades through the public participation movement.